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Kristen and John Magill adore all three of their daughters -- 11-year-old twins and a 5-year-old baby sister. But when they began to plan for their next -- and last -- child, the Magills really wanted a boy.

"My husband is a 'Junior' and has a family business that he wants to continue in the family name," said Kristen, 37, of Grafton, Mass.

So the Magills combined a family trip to Disneyland in August with a stop at a Los Angeles fertility clinic that enables couples to pick the sex of their babies. Kristen is now expecting twin boys.

"I'm excited," she said. "We always wanted a boy. We really wanted just one, but we'll be happy with two."

The Magills are part of a small but growing number of Americans who are selecting the sex of their children, using techniques developed to help couples who are infertile or at risk for having babies with genetic diseases.

In addition to the standard in vitro fertilization procedure that Kristen underwent, a Fairfax clinic is testing another approach that can sort sperm...