In the Spring 2000 newsletter of the National Association of
Writers, Washington Post reporters Deborah Nelson and Rick Weiss
their investigation of the gene therapy experiment at the University
Pennsylvania in which Jesse Gelsinger died.
"How We Uncovered the Hidden Fatality in a Clinical Trial"
the two reporters learned of the death almost serendipitously,
course of a different investigation. They go on to recount how
o the lead investigator, James Wilson, had a clear financial
of interest in the experiment—despite his initial assertion
Weiss that this was not the case;
o the deaths of monkeys treated with a viral vector similar
to the one
that killed Gelsinger had been omitted from the consent form
young man had signed—though the approved version of the
had included it;
o four previous volunteers in the trial had suffered adverse
serious that the study should have been halted—but that
had not even been reported to federal regulators.
National Association of Science Writers, PO Box 294, Greenlawn,