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About Genetic Selection


Genetic selection procedures are done either on fetuses, through prenatal screening, or on embryos that are outside a woman’s body, through Preimplantation Genetic Diagnosis (PGD).

PGD tests embryos for the presence of genetic sequences linked to a variety of conditions and characteristics. A cell is extracted from an embryo at its eight-cell stage and analyzed. Embryos with the selected characteristics can be implanted in a woman's uterus to develop into a child. The procedure does not appear to affect embryos’ or fetuses’ subsequent development, though more follow-up studies of children born after PGD are needed.


Frequently Asked Questions

Arguments Pro & Con

PGD was developed to allow couples at risk of passing on a serious genetic disease to have children not affected by it. Since its introduction in 1990, it has been most widely used to prevent the birth of children with conditions such as Down's syndrome, Tay-Sachs disease, cystic fibrosis, sickle cell, Huntington's chorea, and Cooley's anemia.

However, PGD is increasingly being used for other reasons. These include social sex selection, creating “savior siblings” who can provide bone marrow or other transplant tissues to sick older siblings, and selecting against embryos with genes correlated with late-onset and non-fatal conditions.

A newer variation of PGD, called Preimplantation Genetic Haplotyping, allows for many more genes to be tested, and for greater accuracy.

Many disability rights advocates, in particular, have been critical of PGD and prenatal screening. They point out that the definition of "disease" is to some extent subjective. Most support women’s right to decide whether or not to have a child at a given time, but are critical of basing this decision on the traits of the particular embryo or fetus.



Whither personal genomics?by Jesse ReynoldsBiopolitical TimesJanuary 29th, 2010Three companies offer contrasting examples of where the fledgling industry goes from here.
Embryos destroyed for "minor" disordersby Lois RogersThe TelegraphJanuary 24th, 2010UK fertility regulators are allowing doctors to screen out embryos that could lead full lives despite having a genetic condition.
Nudging the Discourse?by Pete ShanksBiopolitical TimesJanuary 8th, 2010The Popular Mechanics article misleadingly titled "How to Create a Designer Baby" includes a call for regulation of assisted reproduction.
Demand for 'designer babies' to grow dramaticallyby Mark HendersonThe TimesJanuary 7th, 2010Parental demand for “designer babies” screened to lack faulty genes will grow dramatically over the next decade, a leading geneticist has predicted.
IVF websites often mum on embryo gene test risksby Anne HardingReutersOctober 14th, 2009Fertility clinic websites aren't doing a great job of explaining the risks of genetically testing an embryo before it's implanted in the womb, researchers found.
GATTACA Comes to Baseballby Pete ShanksBiopolitical TimesJuly 24th, 2009Major League Baseball has been using DNA tests on prospects from the Dominican Republic.
Preimplantation Genetic Diagnosis May Pose Neurological RisksMedical News TodayJuly 23rd, 2009A new long-term analysis of PGD in mice suggests that it may increase risks of weight gain and memory decline in adulthood.
Other uses for laboratory-produced sperm?by Jesse ReynoldsBiopolitical TimesJuly 13th, 2009Advances in laboratory-produced sperm--if perfected--could also be used for other purposes, including troubling ones.
Healthy Embryos Show Chromosome Flawsby Nora SchultzTechnology ReviewJuly 8th, 2009A study involving higher-resolution genetic screening suggests that PGD often falsely identifies early embryos as unhealthy.
Genetic 'MoT' for disease free babiesby Kate DevlinThe TelegraphJune 30th, 2009A genetic test which can help IVF couples screen embryos for hereditary diseases and have healthy babies could be available within a year.
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