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About Medical Gene Transfer


Sometimes called "gene therapy," medical gene transfer involves adding or modifying genes in a person's cells (other than those found in his or her sperm or eggs). The "new" genes are intended to function in ways that would alleviate a medical condition. They would not be passed on to any future generations.


Arguments Pro & Con

Gene transfer may eventually become an effective treatment for some important medical conditions. Clinical trials have been underway since 1990, but so far have been mostly unsuccessful, involved several conflict-of-interest scandals, and produced adverse results including deaths.

Gene transfer has also been proposed for "enhancement" purposes. This application could raise troubling social and ethical questions.



Biopolitical News of 2016by Pete Shanks, Leah Lowthorp & Marcy DarnovskyBiopolitical TimesDecember 13th, 2016We highlight 2016ís trends in and top news stories about human biotech developments.
Why the hype around medical genetics is a public enemyby Nathaniel ComfortAeonDecember 12th, 2016The progress of science is the steady realisation of how little we actually know. The more we, the public, understand that, the more we will see through the hype.
Setting the record straightby Martin H. JohnsonReproductive BioMedicine OnlineDecember 1st, 2016A senior editor writes about some shoddy scientific journalism on mitochondrial transfer that was published in his own journal.
UK doctors to seek permission to create baby with DNA from three people by Ian SampleThe GuardianNovember 30th, 2016A scientific review concluded that the procedure should be approved for "cautious clinical use" when children are at risk of inheriting specific genetic diseases.
"3-Parent Baby" Procedure Faces New Hurdleby Karen WeintraubScientific AmericanNovember 30th, 2016Mitochondrial disease can somehow creep back in, even if an affected motherís mitochondria are virtually eliminated.
Review of Blame: A Novelby Abby Lippman, Biopolitical Times guest contributorNovember 28th, 2016Blame is especially important for those unfamiliar with the range of ethical, social, legal, and political issues raised by applications of what is learned in a lab. While a work of fiction, it is definitely not science-fiction
DNA-editing breakthrough could fix 'broken genes' in the brain, delay ageing and cure incurable diseasesby Ian JohnstonThe Independent [UK]November 16th, 2016The technique allows DNA changes that have not previously been possible, modifying the genes of non-dividing cells in a living animal.
CRISPR gene-editing tested in a person for the first timeby David CyranoskiNature NewsNovember 15th, 2016A clinical trial in China used cells edited with CRISPR-Cas9 to treat a patient with lung cancer. Spectators anticipate a biomedical duel with US.
Stem Cell Clinics Promise Miracle Cures, but at What Cost to Patients?by Philip PerryBig ThinkNovember 13th, 2016Taking advantage of a regulatory loophole, hundreds of clinics with virtually no oversight are offering stem cell therapies which are virtually untested, and make unsubstantiated claims about helping patients overcome disease.
San Diego Scientists Help Develop New Twist On In Vitro Fertilizationby David WagnerKPBSNovember 10th, 2016The patent holder for a related "3-person IVF" technique reports new work with "polar body genome transfer." Some experts say none of these approaches have been proven safe.
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