Researchers analysed thousands of laboratory-made plasmids and discovered that nearly half of them had defects, raising questions of experimental reproducibility.
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SINGAPORE: The Bioethics Advisory Committee (BAC) is reviewing its current stand against genetic modification with regards to genetic disorders passed on to children by their mothers.
The committee, set up by the Government to deal with issues arising from biomedical sciences research in Singapore, said on Thursday (Apr 19) that it is seeking public feedback and views on whether emerging technology should be allowed to be used to prevent mitochondrial disorders.
Mitochondria are responsible for energy production in cells, and faulty mitochondria can have “serious debilitating effects”, including brain, heart and ear disorders, the committee said.
A public consultation paper put up by the committee - which includes retired chief district judge Richard Magnus, chief executive of Science Centre Singapore Lim Tit Meng and senior consultant at the National Cancer Centre Singapore Professor Kon Oi Lian - looks at the ethical, legal and social issues arising from Mitochondrial Genome Replacement Technology (MGRT).
MGRT, which involves germline modification, a type of genetic modification, has so far not been permitted in Singapore. The BAC recommended against it in 2005 due to the...