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Members of parliament have voted to legalise controversial mitochondrial donation in the first conscience vote since same-sex marriage in 2017.

The legislation, known as Maeve’s law, will legalise partial DNA donations, allowing women to give birth without passing on a genetic disease.

The bill amended the Prohibition of Human Cloning for Reproduction Act 2002 (Cth), and the Research Involving Human Embryos Act 2002 (Cth), and was subject to a conscience vote.

It passed the House of Representatives on Wednesday night, 92 votes to 29.

The prime minister, Scott Morrison, told parliament that the law had been a “difficult issue” to resolve, particularly for those with religious beliefs.

He spoke about the suffering of Kara Crawley who had the disease that had led him to become a patron of the Mito foundation.

“Kara, she died almost five years ago next year, and she died of her 20th stroke” Morrison told parliament.

“She was a beautiful girl. I knew her very well over many years, and I know that her parents Craig and Karen would be very pleased this day.

“Karen...