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It was the 1950s, and Dr. Hudson was trying to prove that prostate cancer could be caught early and cured. But he did not warn the men he was recruiting that the biopsies to search for cancer could cause impotence and rectal tears. Or that the treatment should cancer be found — surgery to remove their prostates and, often, their testicles — had not been proven to prolong life. But he said in a recent telephone interview that he believed the treatments did prolong life. “I told them the cure rate is extremely high,” he said.
As more than 1,200 men living in flophouses on the Bowery signed up for Dr. Hudson’s study in the 1950s and ‘60s, neither his academic peers nor the federal officials overseeing...