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Adrienne Domasin always envisioned someday holding her newborn in her arms. Little did she know that she would make history in the process.

Domasin, 36, of Mission Viejo, gave birth Wednesday evening to the first baby conceived in the United States by means of frozen sperm and a frozen egg, according to Extend Fertility, the firm that sponsored the egg-freezing study in which she took part.

Noah Peter Domasin made his debut at Saddleback Memorial Medical Center in Laguna Hills weighing 8 pounds, 4 ounces. The pain of the hours of labor were minimal compared with the pain Domasin had felt when she was told she couldn't conceive.

Shortly after graduating from USC in 2005, Domasin, who is single, sought other methods to conceive after doctors said her fallopian tubes were blocked.

Her mother said it was "a hard time for her."

"All three of my boys started their families. She was the only one who couldn't have one," said Idanell Domasin, 74.

Unable to afford in vitro fertilization, Domasin, a cinematographer, participated in an Extend-sponsored egg-freezing study at the...