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In November 1988, at a secretive conference center in the woods in Cold Spring Harbor, New York, a select group of biologists, judges, philosophers and others gathered for three days to debate what was then a brand-new practice: the use of DNA in criminal cases.
Also in attendance were two Bronx criminal defense lawyers who knew very little about science. They were there in part because they were working on a murder case in which the prosecutors were planning to present this novel type of evidence—some blood that had been found on the defendant’s wristwatch, containing bands of DNA.
As the first day of the conference dragged into the late afternoon, records of the event show, many of the speakers were expressing great optimism about what was being called “DNA fingerprinting,” saying that it would allow juries for the first time in history to know to a 100 percent certainty whether an accused person is guilty. Then, a brash, brainy young geneticist named Eric Lander—who three decades later is President...