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"The appellate court's judgment that Hwang had concealed and used research funds invested on his research project was justifiable," the top court said in its ruling.
It added that Hwang had violated the Bioethics Law by deducting sterilization fees for women who donating ova during his research.
The conviction of the scientist was confirmed eight years after the stem cell fabrication scandal broke out.
In 2004 and 2005, the veterinarian stunned the science world with papers published in the journal Science that claimed he had developed a stem cell line from cloned human embryos.
But as his research was found to be based on fabricated data, the papers were later retracted and he was prosecuted.
The 59-year-old was indicted on charges of misusing nearly 18 billion won in funds received from the government and two Korean firms ― SK Group and...