3-Person IVF: Overviews and Background
The following links provide broad overviews of "3-person embryos" - the technology, safety and efficacy, and social and ethical considerations. The five resources vary considerably in tone and content.
- FDA Briefing Document- Oocyte Modification in Assisted Reproduction for the Prevention of Transmission of Mitochondrial Disease or Treatment of Infertility
- The Swedish National Council on Medical Ethics English summary of their report on Mitochondria replacement
- Human Genetics Alert's mitochondria briefing
- Nuffield Council on Bioethics' report on mitochondria replacement
- Human Fertilisation and Embryology Authority (HFEA) materials on mitochondria replacement
The following links to a pdf, which includes a summary of national policies on inheritable genetic modification. It is from a testimony given at the House Foreign Affairs Committee Subcommittee on Terrorism, Nonproliferation and Trade by former executive director of CGS, Richard Hayes, Ph.D.
The following two links provide background information on ooplasmic transfer (also called cytoplasmic transfer,) a similar technique to "mitochondrial replacement," attempted for the purpose of treating infertility, that was stopped by the FDA in 2001 due to various problems and concerns.
- Informational page on ooplasmic transfer
- “World's First GM Babies Born”: 12-Year-Old Article Continues to Cause Confusion