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Three teams of scientists said yesterday they had coaxed ordinary mouse skin cells to become what are effectively embryonic stem cells without creating or destroying embryos in the process -- an advance that, if it works with human cells, could revolutionize stem cell research and quench one of the hottest bioethical controversies of the decade.
In work being published today, the scientists describe a method for turning back the biological clocks of skin cells growing in laboratory dishes. Thus rejuvenated, the cells give rise to daughter cells that are able to become all the parts needed to make a new mouse.
If the process also works with human cells, as scientists suspect it will with some modifications, it would mean that a person's own skin cells could be converted directly into stem cells without having to collect healthy human eggs or destroy human embryos -- steps that until now have been required to obtain embryonic stem cells.
Those stem cells could then be used to make a wide variety of personalized replacement tissues.
The findings have generated tumult on Capitol...