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Stem cell research in the United States has been hobbled for years by severe and misguided restrictions on federal funding. But now a vexing additional problem is slowing even privately financed research. There are distressingly few women willing to donate their eggs for experiments at the frontiers of this promising science.

A respected team of stem cell researchers at Harvard spent nearly $100,000 over the course of a year advertising for egg donors. Hundreds of qualified women were interested enough to call but, after hearing what was entailed, not one was willing to donate eggs. Many were likely deterred by the time, effort and pain required - including daily hormone injections and minor surgery - to retrieve the eggs. And they were almost certainly discouraged by the meager compensation.

Although women can be paid thousands of dollars to donate eggs for fertility treatments, ethical guidelines and some state laws say they cannot be paid much for donating to research. These restrictions are meant to protect the women against exploitation, but they have created a dearth of egg donors for stem...