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Elite athletes do whatever it takes to win. Lately, that’s meant getting an injection of their own stem cells.

The treatments, developed over the last eight years, typically involve extracting a small amount of a player’s fat or bone marrow and then injecting it into an injured joint or a strained tendon to encourage tissue regeneration. Bone marrow contains stem cells capable of generating new blood cells, cartilage, and bone.

Although the treatments have become a multimillion-dollar industry, some doctors say there’s only thin medical evidence they actually speed healing. In a report issued last week, public policy researchers at Rice University criticized the National Football League’s role in promoting “unproven” treatments to the public. Some players, including Peyton Manning of the Denver Broncos and Sidney Rice, who’s now retired but won a Super Bowl with the Seattle Seahawks last year, have reportedly gone overseas for stem cell treatments and others have acted as spokespeople for U.S. clinics offering them.

The Rice researchers, Kirstin Matthews and Maude Cuchiara, say the NFL should create an independent panel and fund...